설탕을 대체할 수 있지만 역시 적절한 양을 섭취해야 한다. 아스파탐과 수크랄로스와 같은 인공 감미료는 장내 박테리아에 영향을 미쳐 특히 좋은 감미료와 나쁜 감미료의 균형을 변화시킨다. 이는 영양소 흡수와 신진대사에 영향을 미친다는 연구 결과가 있다.
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